Description
Wpp Dianabol 10mg is a specific formulation of methandienone, also known as methandrostenolone. It is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone . The 10mg tablet strength is a common dosage for research purposes, with regulatory approvals for export use documented in some jurisdictions . It is also marketed under trade names such as DIABOL-10 and MEDANABOL in certain regions
.
Its chemical name is 17α-methyl-17β-hydroxy-1,4-androstadien-3-one, with the molecular formula C₂₀H₂₈O₂ and a molecular weight of 300.4 g/mol
. The compound features a unique Δ1 double bond and a 17α-methyl group, which allows for oral bioavailability by reducing first-pass metabolism, but also contributes to its liver toxicity
.
Mechanism of Action and Research Applications
Dianabol exerts its primary effects through binding to and activating the androgen receptor (AR)
. It has a distinctive anabolic:androgenic dissociation index of approximately 2-3, and relative to testosterone’s baseline of 100:100, its ratio is characterized as 200:50 . This indicates that it is about twice as anabolic as testosterone but only half as androgenic, making it a potent agent for muscle growth research
.
Additionally, research suggests that methandienone may affect cortisol metabolism by inhibiting its hepatic detoxification, which could contribute to its muscle-building properties
. It has been studied for conditions characterized by muscle wasting, as well as for treating osteoporosis and promoting nitrogen retention
.
Critical Safety Concerns and Toxicity
Despite its research potential, Wpp Dianabol 10mg carries severe and well-documented safety risks, particularly concerning liver health
.
Hepatotoxicity: Methandienone is associated with significant drug-induced liver injury (DILI)
. A 2026 study found that exposure to methandienone induced liver injury characterized by hepatocyte steatosis and inflammation, accompanied by significant increases in serum ALT and AST . In one study, cell viability decreased to 88.01% after 24 hours of treatment, and the apoptosis rate increased to 25.08%
.
Fatal cases have also been documented. A case report from 1962 detailed a 71-year-old woman who developed fatal cholestatic jaundice and liver failure after using methandrostenolone for osteoporosis. Autopsy revealed a shrunken liver with extensive biliary cholangiolytic plugging
. Consequently, researchers must treat this compound with extreme caution.
Other Adverse Effects: Long-term use can lead to changes in cholesterol levels, hormonal imbalances, and potential hypothalamic-pituitary-gonadal axis disruption
.
Regulatory Status and Prohibition
Wpp Dianabol 10mg is a strictly controlled substance in most countries. It is explicitly listed on the World Anti-Doping Agency (WADA) Prohibited List under class S1.1 as an Anabolic Androgenic Steroid
. Consequently, its use in athletic competition is strictly forbidden, and athletes have received significant bans for its use . It is available only for research purposes in controlled laboratory settings or as an export-only product under specific regulatory frameworks
.
Conclusion
In summary, Wpp Dianabol 10mg is a potent research compound with a well-characterized mechanism of action via androgen receptor activation. However, its significant potential for severe hepatotoxicity and other adverse effects makes it a high-risk substance. Researchers must treat it with extreme caution and adhere strictly to safety protocols. Its WADA-prohibited status further reinforces its strictly controlled nature.





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